We develop versatile molecular imaging methods, focusing on innovative fluorescent biosensors for visualizing protein dynamics and conformation in live cells. Our work includes creating vivid dyes for protein conformation reporting and designing modifiable domains for protein function control via light or small molecules.

We create top-tier light-sheet microscopes, tailored for multiplexed biosensor imaging in live cells. Designed for widespread use, our microscopes feature a user-friendly, highly engineered optical path and come with sophisticated control software for analysis-ready data output.

We focus on crafting technologies for analyzing cell functionality and its regulation through cytoskeletal and signaling networks. Utilizing advanced computational techniques, we deliver precise, comprehensive insights into cellular biology. Our approaches decode intricate, multi-dimensional cell processes.